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Sleep Inn Orangeburg

3689 Saint Matthews Rd, Orangeburg, SC 29118

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Every room at the Sleep Inn® hotel in Orangeburg is a simply stylish sanctuary designed for a dreamy night’s sleep. We are conveniently located near South Carolina State University and Claflin University. Make yourself at home in your cozy guest room, which features a restful bed, a flat-screen TV, free WiFi, a coffee maker, microwave, refrigerator, and a large desk space. Start your day with our free hot breakfast featuring assorted baked goods, waffles, juices and coffee. Read more

Situated at St. Mathews Road and I-26, our hotel offers easy access to popular destinations, including Edisto Memorial Gardens, Elloree Heritage Museum and Cultural Center, Southern Methodist College, Calhoun County Museum, and Orangeburg–Calhoun Technical College. We’re also close to camping, hiking and biking trails at Santee State Park, and excellent fishing at Lake Marion, which is known for its abundant population of large catfish. The state capital, Columbia, and Columbia Metropolitan Airport are both within 45 minutes from our hotel.

After a day of outdoor adventures, watching college sports, or playing a round of golf at Hillcrest Golf Course, unwind with a swim in our seasonal outdoor pool. If you’re looking for a hotel close to great recreation, book your stay at the Sleep Inn hotel in Orangeburg.

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Rates as of 10/05/2025 06:40 AM (PST)

Online Rates $129.00 (+Tax)

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King Room - Non-Smoking

Based on availability

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3689 Saint Matthews Rd, SC 29118

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Amenities

  • Alarm clock
  • Toilet
  • Interconnecting room(s) available
  • Telephone
  • Hairdryer
  • Cable channels
  • Carpeted
  • Wake-up service
  • Desk
  • Microwave
  • Refrigerator
  • Heating
  • Shower
  • Iron
  • Radio

Nearby Attractions and Restaurants


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